FENG LILI,GONG BAOQING,KARPINSKI PIOTR H.,WAYKOLE LILADHAR MURLIDHAR
申请号：
NZ61071311
公开号：
NZ610713A
申请日:
2011.12.15
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
The disclosure relates to crystalline forms of 5-chloro-N2-(2-isopropoxy-5-methyl-4-piperidin-4-yl-phenyl)-N4[2-(propane-2-sulfonyl)-phenyl]-pyrimidine-2,4-diamine. Two such forms have melting points at 174 degrees C and 162 degrees C as determined by differential scanning calorimetry. The disclosure also relates to methods for preparing said crystalline forms, pharmaceutical compositions comprising said crystalline forms, and methods of using said crystalline forms and pharmaceutical compositions to treat diseases mediated by anaplastic lymphoma kinase.
