The United States of America;as represented by the Secretary; Department of Health & Human Services
发明人:
Bira Arya,Purevdorj Olkhanud,Juan Espinoza
申请号:
US14220726
公开号:
US20140377179A1
申请日:
2014.03.20
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention features compositions and methods that make use of complexes comprising one or more inhibitory nucleic acids and a targeting polypeptide, wherein the targeting polypeptide consists of a cell surface receptor ligand. The compositions can be used in methods of silencing gene expression in a cell, in delivering agents to a target cell, and in treating or preventing a disease or disorder in a subject.