University of Saskatchewan;Bioniche Life Sciences Inc.
发明人:
Potter, Andrew A.,Asper, David,Rogan, Dragan
申请号：
AU2010234193
公开号：
AU2010234193B2
申请日:
2010.04.06
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
Compositions and methods for stimulating an immune response against Shiga toxin-producing Escherichia coli (STEC) antigens are disclosed. The compositions include a multiple epitope fusion protein comprising more than one epitope of an immunogenic STEC protein from more than one STEC serotype. Additional compositions include at least two purified STEC proteins, wherein the STEC proteins are selected from a full-length STEC protein, an immunogenic fragment or variant thereof, wherein at least one of the STEC proteins generates antibodies that react with STEC 0157 and at least one other STEC serotype.
