The present invention relates to antigen binding proteins, such as antibodies, which bind to serum amyloid P component (SAP), polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. The present invention also concerns the use of such antigen binding proteins in the treatment or prophylaxis of diseases associated with amyloid deposition including systemic amyloidosis, local amyloidosis, Alzheimers disease, and type 2 diabetes.本發明係關於結合於血清澱粉樣蛋白P組分(SAP)之抗原結合蛋白,諸如抗體,編碼該等抗原結合蛋白之聚核苷酸,包含該等抗原結合蛋白之醫藥組合物,及製造方法。本發明亦關於該等抗原結合蛋白於治療或預防與澱粉樣蛋白沈積有關之疾病(包括全身性澱粉樣變性、局部澱粉樣變性、阿茲海默氏病(Alzheimers disease)及2型糖尿病)的用途。(無元件符號說明)
