RYAN M. MOSLIN,DAVID S. WEINSTEIN,STEPHEN T. WROBLESKI,JOHN S. TOKARSKI,AMIT KUMAR,DOUGLAS G BATT,SHUQUN LIN,CHUNJIAN LIU,STEVEN H. SPERGEL,YANLEI ZHANG
申请号:
PT13811640
公开号:
PT2922846T
申请日:
2013.11.07
申请国别(地区):
PT
年份:
2018
代理人:
摘要:
Compounds having the following formula I:or a stereoisomer or pharmaceutically-acceptable salt thereof, where R, R, R, R, and Rare as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.