Disclose the bispecific antibody of the antibody and antigen-binding fragment and the toxin for being also coupled to secretion including these antibody or binding fragment for staphylococcus aureus (S.aureus) surface epitopes antigen. Additionally provide the method using these antibody and antigen-binding fragment detection, diagnosing and treating infection of staphylococcus aureus. Further disclose the heavy chain variable region (VH) and light chain variable region (VL) region sequence of these antibody.披露了針對金黃色葡萄球菌(S.aureus)表面決定簇抗原的抗體和抗原結合片段以及包括這些抗體或結合片段的還結合至分泌的毒素的雙特異性抗體。還提供了使用這些抗體和抗原結合片段檢測、診斷和治療金黃色葡萄球菌感染的方法。進一步披露了這些抗體的重鏈可變區(VH)和輕鏈可變區(VL)區序列。
