Barrett Allan,Kristine Kay Kikly,Derrick Ryan Witcher
申请号:
US15079184
公开号:
US09951146B2
申请日:
2016.03.24
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Bispecific antibodies are provided that bind CD20 and B-cell Activating Factor of the TNF Family (BAFF) and are characterized as having high affinity and strong simultaneous neutralizing properties to both CD20 and BAFF. The bispecific antibodies of the invention are useful for treating autoimmune diseases including Systemic Lupus Erythematosus, Lupus Nephritis, and primary Sjögren's Syndrome.