Liangqin Guo,William K. Hagmann,Shuwen He,Zhong Lai,Jian Liu,Ravi P. Nargund,Shrenik K. Shah,Quang T. Truong
申请号:
US13518015
公开号:
US20120264777A1
申请日:
2011.01.11
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Beta-carboline derivatives of structural formula I are selective antagonists of the somatostatin sub-type receptor 3 (SSTR3) and are useful for the treatment of Type 2 diabetes mellitus and of conditions that are often associated with this disease, including hyperglycemia, insulin resistance, obesity, lipid disorders, and hypertension. The compounds are also useful for the treatment of depression and anxiety.