The present disclosure relates to a method for determining an interest in applying a Quality Assessment (QA) procedure to a proposed treatment plan in radiation therapy. In one implementation, the method includes receiving information relating to a proposed treatment plan; receiving information relating to a reference treatment plan that complies with a quality criterion; obtaining a dose distribution resulting from the reference treatment plan and/or a parameter of the reference treatment plan; obtaining a dose distribution resulting from the proposed treatment plan and/or a parameter of the proposed treatment plan; comparing the dose distribution resulting from the proposed treatment plan with the dose distribution resulting from the reference treatment plan and/or comparing the parameter of the proposed treatment plan with the same parameter of the reference treatment plan; and determining an interest of applying a QA procedure to the proposed treatment plan based on the comparison.