Anne S De Groot,William D Martin,Yoshimasa Takahashi,Manabu Ato
申请号:
US15571042
公开号:
US20180179256A1
申请日:
2016.04.15
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention is directed to a sequence modification of the H7 hemagglutinin glycoprotein of the Influenza A/Shanghai/2/2013 H7 sequence together with vaccines derived therefrom. In addition, the invention further comprises method for improving the efficacy of vaccine antigens by modifying T cell epitopes.