Soonchunhyang University Industry Academy Cooperation Foundation
发明人:
申请号:
EP15814748.8
公开号:
EP3162792A4
申请日:
2015.06.30
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention provides a preparation method for agomelatine-resorcinol and agomelatine-hydroquinone co-crystals using the solvent-antisolvent method that enables a commercial mass production. The co-crystals prepared by the preparation method of the present invention displays high dissolution rate and high stability in acidic-to-neutral media.