#$%^&*AU2013204904A120130516.pdf#####H:\rbr\lnteroven\NRortbl\DCC\RBR\5074193_1.doc-4/12/2013 ABSTRACT The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the 5 invention and methods of using the compositions in the treatment of various diseases.