A portable mechanical ventilator having a Roots blower provides a desired gas flow and pressure to a patient circuit. The mechanical ventilator includes a flow meter operative to measure gas flow produced by the Roots blower and an exhalation control module configured to operate an exhalation valve connected to the patient circuit. A bias valve connected between the Roots blower and the patient circuit is specifically configured to generate a bias pressure relative to the patient circuit pressure at the exhalation control module. The bias valve attenuates pulsating gas flow produced by the Roots blower such that gas flowing to the mass flow meter exhibits a substantially constant pressure characteristic. The bias pressure facilitates closing of the exhalation valve at the start of inspiration, regulates positive end expiratory pressure during exhalation, and purges sense lines via a pressure transducer module.
