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Cryopreservation of apoptotic cancer cells for use in immunotherapy against cancer
专利权人:
SOTIO a.s.
发明人:
Jitka Fucikova,Lenka Koci,Katerina Pokorna,Iva Truxova,Irena Moserova,Daniela Rozkova,Radek Spisek
申请号:
US15388972
公开号:
US09895430B2
申请日:
2016.12.22
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Described herein is a reliable method for preparing a potent vaccine useful for immunotherapy comprising the step of cryopreserving a population of cells undergoing immunogenic cell death, and using such cells to activate dendritic cells for use in immunotherapy. In a specific embodiment, the method comprises cryopreserving cancer cells undergoing cell death, which can be used to prepare a pharmaceutical composition for immunotherapy against cancer.
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