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Preparation of Technetium-99M Tricarbonyl Labeled Glycine Monomer or Oligomer Containing Probes That Have Biomolecules and Its Application as Imaging Complex-Composition
专利权人:
发明人:
Beom Su Jang,Sang Hyun Park,Joo-Sang Lee,Jong-Kook Rho
申请号:
US14399431
公开号:
US20150151011A1
申请日:
2013.05.13
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed is a technetium-99m-labeled glycine oligomer associated with imaging probes for biomolecules of interest. The glycine oligomer can be readily synthesized in a single process using an automated peptide synthesizer. The technetium-99m tricarbonyl-labeled glycine oligomers can be useful as a radiotracer for gamma or SPECT imaging apparatus. The technetium-99m tricarbonyl-labeled glycine oligomers can be applied to various peptidyl biomolecules such as RGD peptide, somatostatin, neurotensin, etc., and exhibit rapid renal clearance without being excessively retained within the body.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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