Sumith A. Kularatne,Philip S. Low,Pravin Gagare,Carrie Myers
申请号：
US14937169
公开号：
US20170065729A1
申请日:
2015.11.10
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present disclosure relates to prostate specific membrane antigen (PSMA) targeted compounds conjugated to near-infra red (NIR) dyes and methods for their therapeutic and diagnostic use. More specifically, this disclosure provides compounds and methods for diagnosing and treating diseases associated with cells and/or vasculature expressing prostate specific membrane antigen (PSMA), such as prostate cancer and related diseases. The disclosure further describes methods and compositions for making and using the compounds, methods incorporating the compounds, and kits incorporating the compounds.
