The present invention relates to an ophthalmic composition which is an aqueous composition having pH between 7 and 7.4, osmolarity between 280 and 300 mOsm/1, and which comprises one or more glycosaminoglycans (GAGs), wherein said composition has a contact angle measured over a Kapton surface in the range of about 50° and 80°.In a further aspect, said composition is claimed for use in the epithelial protection in femto-assisted eye surgery.