Being the antagonist of the CGRP receptor, at the time of the remedy or preventing of the disease (for example, migraine) where CGRP participates the usefulness, with as formula, the chemical compound which (i) (in formula, as for variable element B, G, G, G, G, E, E, E, A, A, A, A, R and R and Y, defined in this bill is,) is displayed. As for this invention, furthermore, it regards also aforementioned chemical compound and the use of the constituent in the medicine constituent, and the prevention or remedying which of the aforementioned disease where CGRP participates include aforementioned chemical compound.< Conversion 1 >CGRP受容体のアンタゴニストであって、CGRPが関与する疾患(例えば、偏頭痛)の治療又は予防において有用な、式(I)〔式中、可変要素B、G1、G2、G3、G4、Ea、Eb、Ec、A1、A2、A3、A4、R6及びRPG並びにYは、本明細書中で定義されている通りである〕で表される化合物。本発明は、さらに、前記化合物を含んでいる医薬組成物、並びに、CGRPが関与する前記疾患の予防又は治療における前記化合物及び組成物の使用にも関する。【化1】
