MEDPROJECT PHARMA-ENTWICKLUNGS- UND VERTRIEBSGESELLSCHAFT MBH
发明人:
HEINZ POLZER,HEINZ POLZER,HEINZ POLZER,JÜRGEN SENGE,JÜRGEN SENGE,JÜRGEN SENGE,PIERRE-PAUL ELENA,PIERRE-PAUL ELENA,PIERRE-PAUL ELENA
申请号：
BR112017026552
公开号：
BR112017026552A2
申请日:
2016.06.08
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
The invention refers to a drippable ophthalmic gel, said gel having a composition comprising bimatoprost in an amount of 0.003 to 0.03% by weight, polyacrylate in an amount of 0.15 to 0.7% by weight, povidone (PVP), dextrane, polyethylene glycols (PEG), carboxymethyl cellulose (CMC) or poly(vinyl alcohol) (PVA) in an amount of 0.2 to 0.8 % by weight, an isotonizing agent in an amount to produce an osmolality of 200 to 400 mosml/kg, a salt for adjusting the viscosity in an amount of 0.05 to 0.4% by weight, a base in an amount to adjust the pH to 6 to 8 and excipients normally used in ophthalmic gels.
