Disclosed are an ultrasound diagnosis apparatus and a method of operating the same. The ultrasound diagnosis apparatus includes a data acquirer that acquires ultrasound data about an object, an image processor that generates an ultrasound image, based on the ultrasound data and generates a first marker for a first object of interest (OOI) which is not included in the generated ultrasound image, and a display that displays the generated ultrasound image and marks the first marker to correspond to a position of the first OOI.
