MESSINA, LUCIANO,VACCARO, SUSANNA,CARUSO, SALVATORE,GENNARI, GIOVANNI
申请号:
DK10718616
公开号:
DK2432874T3
申请日:
2010.05.12
申请国别(地区):
DK
年份:
2015
代理人:
摘要:
The invention relates to Streptomyces koganeiensis ATCC 31394 hyaluronidase having molecular weight of 21.6 kDalton, which has hyaluronidase activity and stability markedly higher than those of the hyaluronidase obtained from such microorganism to date. The invention further relates to a process for the isolation and purification of said hyaluronidase and its use for the preparation of pharmaceutical compositions or as an analytical reagent.