A medication management system (100) for controlling access to medication. The system (100) comprises of a portable, electronically locking cassette (102) and a docking station (104). The cassette (102) comprises at least one internal compartment (110) adapted for storing patient-specific medication, a cover (114) adapted for restricting access to said compartment (110), a locking mechanism (112) for securing said cover (114), and means for storing a cassette identifier associated with said cassette. The docking station (104) comprises means for storing at least one authorized cassette identifier and at least one authorized user identifier, an input device (140) for receiving a user identifier, a cassette identifier, and a function identifier, and a controller (500B) for coupling said cassette (102) dependent upon said cassette identifier and said at least one authorized cassette identifier, validating a received user identifier and a received cassette identifier based upon said at least one authorized user identifier and said at least one authorized cassette identifier, operating said locking mechanism (112) based upon a received function identifier and said validation, and uncoupling said cassette (102) dependent upon said validation.L'invention concerne un système de gestion de médicaments (100) destiné à commander l'accès à des médicaments. Le système (100) comprend une cassette portable à verrouillage électronique (102) et une station de rangement (104). La cassette (102) comprend au moins un compartiment interne (110) conçu pour stocker un médicament spécifique d'un patient, un couvercle (114) conçu pour restreindre l'accès au compartiment (110), un mécanisme de verrouillage (112) conçu pour fixer le couvercle (114) et des moyens de stockage d'identificateur de cassette associés à la cassette. La station de rangement (104) comprend des moyens de stockage d'au moins un identificateur de cassette autorisé et d'au moins un identificateur d'utilisateur autorisé ;