A device (1) for the application of cold comprising a bag (2) divided by removable separation means (3) into two compartments (2a, 2b) hermetically separated from one another. In the first compartment (2a), it houses a solid composition comprising a compound designed to solubilize in an endothermic way in water and a substance designed to favour the formation of a gel by means of modulation of pH and/or of ionic force of an aqueous solution, whereas in the second compartment (2b) it houses an aqueous solution comprising water and a gelling substance.
