An image pickup apparatus for endoscope includes: an image pickup optical system a right angle prism configured to receive light from the image pickup optical system and an image pickup substrate rectangular in plan view with a thickness equal to or greater than 20 μm and equal to or smaller than 100 μm, in which the right angle prism is adhered to a first main surface 60SA, and a light receiving portion is formed below the right angle prism, wherein a groove is formed on a second main surface of the image pickup substrate, and a direction of the groove is inclined more than 45 degrees relative to a short axis direction.
