Nuclease resistant double-stranded ribonucleic acid

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专利权人:

Alnylam Pharmaceuticals; Inc.

发明人:

Roehl, Ingo,Rajeev, Kallanthottathil G.,Zimmermann, Tracy Stage,Vornlocher, Hans-Peter,Akinc, Akin,Hadwiger, Philipp,Manoharan, Muthiah

申请号：

AU2005247509

公开号：

AU2005247509C1

申请日:

2005.05.27

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

This invention relates to modified double-stranded oligoribonucleic acid (dsRNA)having improved stability in cells and biological fluids, and methods of makingand identifying dsRNA having improved stability, and of using the dsRNA to inhibitthe expression or function of a target gene.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/