Kularatne, Sumith A.,Low, Philip S.,Gagare, Pravin,Myers, Carrie
申请号：
AU2016318949
公开号：
AU2016318949A1
申请日:
2016.09.08
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The present disclosure relates to prostate specific membrane antigen (PSMA) targeted compounds conjugated to near-infra red (NIR) dyes and methods for their therapeutic and diagnostic use. More specifically, this disclosure provides compounds and methods for diagnosing and treating diseases associated with cells and/or vasculature expressing prostate specific membrane antigen (PSMA), such as prostate cancer and related diseases. The disclosure further describes methods and compositions for making and using the compounds, methods incorporating the compounds, and kits incorporating the compounds.
