MEANS OF CONTROLLING INFECTION PERSISTENCE OF HELICOBACTER PYLORI

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专利权人:

发明人:

申请号：

EP11797396.6

公开号：

EP2585584A1

申请日:

2011.06.24

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present invention relates to a means of controlling infection persistence of Helicobacter pylori (H. pylori). In particular, the present invention relates to an isolated, genetically modified Helicobacter pylori comprising a functional urease, wherein the contiguous amino acid sequence between amino acid 529 and amino acid 555 of SEQ ID NO:1 is altered to produce said modified Helicobacter pylori which is unable to establish or maintain a persistent infection.

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