Cell preparation depleted of TCR alpha / beta

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专利权人:

ミルテニイ バイオテック ゲゼルシャフト ミット ベシュレンクテル ハフツング

发明人:

ハントグレティンガー，ルパルト,ヒュッペルト，フォルカー,ハントグレティンガー,ルパルト,ヒュッペルト,フォルカー

申请号：

JP2013558470

公开号：

JP5955871B2

申请日:

2012.03.19

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

The invention relates to a composition, comprising a cell population that can be obtained from bone marrow or from blood, when the cell population is depleted of cells that express TCR alpha/beta and cells that express CD19. Such a pharmaceutical composition makes the reconstitution of the immune defense of a person as part of a bone marrow transplantation possible. By means of the invention, the time until the immune reconstitution is considerably shortened and the immune response after treatment are considerably reduced, in particular the occurrence of GvHD. The survival rate of the patient is considerably increased.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/