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3-arylamino pyridine derivatives
专利权人:
Merck Serono SA
发明人:
Schwarz, Matthias,Thiemann, Meinolf,Gradler, Ulrich,Otte, Kerstin,Deppe, Holger,Jiang, Xuliang,Goutopoulos, Andreas,Feurer, Achim,Abel, Ulrich,Sekul, Renate
申请号:
AU2005298932
公开号:
AU2005298932B2
申请日:
2005.10.19
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The invention provides novel, substituted 3-arylamino pyridine compounds(I) pharmaceutically acceptable salts, solvates and prodrug compounds thereof,wherein W, R1, R2, R9, R10, R11, R12, R13, R14 are as defined in the specification.Such compounds are MEK inhibitors and useful in the treatment of hyperproliferativediseases, such as cancer, restenosis and inflammation. Also disclosed is theuse of such compounds in the treatment of hyperproliferative diseases in mammals,especially humans, and pharmaceutical compositions containing such compounds.
来源网站:
中国工程科技知识中心
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