Oleksandr Prokopovyeh Kozynchenko;Anthony Paul Rawlinson;Gary James Phillips;Carol Angela Howell;Sergey Victorovich Mikhalovsky;Stephen Robert Tennison;Susan Rachel Sandeman
发明人:
Stephen Robert Tennison,Oleksandr Prokopovyeh Kozynchenko,Anthony Paul Rawlinson,Gary James Phillips,Carol Angela Howell,Susan Rachel Sandeman,Sergey Victorovich Mikhalovsky
申请号：
US13513340
公开号：
US20130072845A1
申请日:
2010.12.09
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Whole blood is treated extracorporeally to remove substances contrary to health using mesoporous/microporous or macroporopus/microporous carbon in the form of beads or a channel monolith. The carbon may be the result of carbonising a mesoporous or macroporous phenolic resin. Substances contrary to health include externally introduced toxins such as bacterially derived staphylococcus enterotoxins A, B, TSST-1 or autologous, biologically active molecules with harmful, systemic effects when their activity is excessive or unregulated. Examples include the removal of inappropriate amounts of pro- or anti-inflammatory molecules and toxic mediators of systemic inflammatory response syndrome related to sepsis, cardio-pulmonary by-pass surgery, ischaemic reperfusioninjury； the removal of larger molecular weight and protein bound uremic toxins related to kidney and hepatic toxins related to liver failure and the removal of toxins relevant to biological and chemical warfare.
