The Trustees of the University of Pennsylvania;Fondazione IRCCS Istituto Nazionale dei Tumori
发明人:
Daniel J. Powell,George Coukos,Mariangela Figini,Silvana Canevari
申请号：
US16594871
公开号：
US20200270341A1
申请日:
2019.10.07
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention provides compositions and methods for treating ovarian cancer. Specifically, the invention relates to administering a genetically modified T cell having α-folate receptor (FRα) binding domain and 4-1BB (CD137) costimulatory domain to treat ovarian cancer.
