The present subject matter relates to a preservative or antimicrobial compositions which comprise low concentrations of botanical extracts, in synergistic combinations with alkanediols in a solvent system, optionally with fruit acids. Additionally, the present subject matter relates to a preservative or antimicrobial compositions which comprise a silver compound, an essential oil or individual constituent, one or more zinc salts, and one or more alkanediol. The compositions of the application may be used in personal care products including wound care products or in veterinary use. Preferably, the compositions of the application have little or no human-detectable fragrance.