The invention relates to a lubricant coating (5) for a medical injection device (1) , comprising successively: a bottom layer (50) in contact with the medical device surface (21) of the container to be lubricated comprising a mixture of cross- linked and non -cross- linked poly -(dimethylsiloxane),- an intermediate layer (51) consisting essentially of oxidized poly (dimethylsiloxane) and having a thickness comprised between 10 and 30 nm and ,- a top layer (52) consisting essentially of non cross linked poly (dimethylsiloxane) and having a thickness of at most 2 nm. The invention also relates to a medical injection device comprising such a lubricant coating, and a manufacturing process for said coating.
