ЗЕРБЕ Хорст Г. (CA),АНГУСТИ Анджела (CA),ПЕАМАН Надин (CA)
申请号：
RU2016106907
公开号：
RU2016106907A
申请日:
2014.07.30
申请国别(地区):
RU
年份:
2017
代理人:
摘要：
An instantly wettable and rapidly disintegrating oral film dosage form without a surfactant and without a polyalcohol was achieved by combining at least one water soluble polymer that is not a copolymer of vinylpyrrolidone, at least one active agent, a copolymer of vinylpyrrolidone and titanium dioxide. In certain embodiments, the film comprises hydroxypropyl cellulose or a combination of hydroxypropyl cellulose and a polymer or copolymer of vinylpyrrolidone or a substituted vinylpyrrolidone as the water soluble polymer(s). A plasticizer, and optional additives selected from synthetic sweeteners, natural sweeteners, flavorants, antioxidants, colorants, and opacifiers, can be added to the disclosed film oral dosage forms.
