ALVOCIDIB PRODRUGS HAVING INCREASED BIOAVAILABILITY

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专利权人:

发明人:

SIDDIQUI JAIN ADAM,BEARSS DAVID J

申请号：

IN201717040897

公开号：

IN201717040897A

申请日:

2017.11.15

申请国别(地区):

IN

年份:

2018

代理人:

摘要：

Compounds having the following structure (I): or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein one of R1, R2 or R3 is -P(=0)(OH)2, and the other two of R1, R2 and R3 are each H, are provided. Pharmaceutical compositions comprising the com pounds, and methods for use of the compounds for treating diseases associated with overexpression of a cyclin-dependent kinase (CDK) are also provided

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