Ulrik Nielsen,Thomas Wickham,Birgit Schoeberl,Brian Harms,Bryan Linggi,Matthew Onsum,Byron DeLaBarre,Shaun M. Lippow
申请号:
US16524451
公开号:
US20200048368A1
申请日:
2019.07.29
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair or regenerate damaged or diseased tissue. The bi-specific fusion proteins generally comprise: (a) a targeting polypeptide domain that binds to a target molecule; and (b) an activator domain that detectably modulates tissue regeneration.