Systems and methods are taught for non-invasively monitoring brainstem function and intra-cranial pressure in a patient. Repeated auditory stimulation is applied to the patient in at least one ear to generate an auditory brainstem response. The response waveform is detected with an electrode at a location on the patients head. The detected waveform data is compared with known waveform data and an alarm is initiated when a change in the auditory brainstem response is detected based on the comparison that is indicative of a corresponding change in intra-cranial pressure in the patient.