Phenylaminopyrimidine bicyclic compounds and uses thereof

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专利权人:

ワイエム・バイオサイエンスィーズ・オーストラリア・ピーティーワイ・リミテッド

发明人:

バーンズ， クリストファー ジョン,バーンズ, クリストファー ジョン

申请号：

JP2015518724

公开号：

JP5931288B2

申请日:

2013.06.26

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

The present invention relates to phenyl amino pyrimidine bicyclic compounds formula I which are inhibitors of protein kinases including JAK kinases. In particular the compounds are active against JAK1, JAK2, JAK3 and TYK2 kinases. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants； hyperproliferative diseases including cancer and myeloproliferative diseases； viral diseases； metabolic diseases； and vascular diseases.

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