Ulm University;The Regents of the University of California
发明人:
BALIN, Samuel J.,MODLIN, Robert L.,STENGER, Steffen,PELLEGRINI, Matteo
申请号：
EP17779615
公开号：
EP3439688A4
申请日:
2017.04.04
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
Various aspects of the invention relate to compositions comprising polycytotoxic T cells. Some aspects relate to methods for obtaining a composition comprising polycytotoxic T cells. Some aspects relate to methods of administering a composition comprising polycytotoxic T cells to a subject. Some aspects relate to methods for monitoring an immune response in a subject, comprising determining the concentration of polycytotoxic T cells in the blood of the subject. Some aspects relate to methods for treating a condition or disease in a subject, comprising administering to the subject a composition comprising an antibody, or an antigen-binding portion thereof, that specifically binds to a protein expressed by a polycytotoxic T cell.
