BHAKTA, SUNIL,ERICKSON, HANS,JUNUTULA, JAGATH R.,KOZAK, KATHERINE,OHRI, RACHANA,PILLOW, THOMAS
申请号：
SG11201701128Y
公开号：
SG11201701128YA
申请日:
2015.09.11
申请国别(地区):
SG
年份:
2017
代理人:
摘要：
Cysteine engineered antibodies comprising a free a cysteine at position 140 according to EU numbering in the heavy chain are generated. These antibodies are prepared by mutagenizing a nucleic acid sequence of a parent antibody to introduce a A140C mutation； expressing the cysteine engineered antibody； and isolating it.
