NOUVEAUX VECTEURS VIRAUX ADENO-ASSOCIES RECOMBINES LIMITANT LA TRANSDUCTION HORS CIBLE DANS LE FOIE ET LEURS UTILISATIONS

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专利权人:

OHIO STATE INNOVATION FOUNDATION

发明人:

CAO, LEI,HUANG, WEI

申请号：

CA3057680

公开号：

CA3057680A1

申请日:

2018.03.26

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

Disclosed are compositions and methods related to novel adeno-associated virus vectors comprising two expression cassettes, wherein the first cassette comprises a regulatory element and a transgene operatively linked to a promoter； and wherein the second cassette comprises a liver specific promoter operatively linked to a microRNA that targets the regulatory element in the first expression cassette.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/