ATOMIC ENERGY COUNCIL-INSTITUTE OF NUCLEAR RESEARCH
发明人:
CHANG, CHIA JUNG,张家荣,張家榮,CHOU, WEI KANG,周玮纲,周瑋綱,YANG, AN SHOEI,杨安水,楊安水,LIAO, MEI HSIU,廖美秀,廖美秀,SHEN, LIE HANG,沈立汉,沈立漢
申请号：
TW101130730
公开号：
TW201408623A
申请日:
2012.08.23
申请国别(地区):
TW
年份:
2014
代理人:
摘要：
An automated synthesis system for iodine-123-IBZM nuclear medicine includes a control/display means, a reactant supply means connecting to the control/display means an adsorption means connecting to the control/display means and to the reactant supply means, an oxidation means connecting the control/display means, the reactant supply means and the adsorption means, a product collection means connecting to the control/display means, the reactant supply means, the adsorption means and the oxidation means a waste liquid collection means connecting to the control/display means, the adsorption means and the product collection means, and a gas filtration means connecting the control/display means, the oxidation means and the product collection means. This system can automate the processing steps needed for marking, such as oxidation, reduction, neutralization, adsorption, washing, elution etc, and reduce the hand operating time, the exposure dose to radiation, the mistakes and deviations while stabilize the product quality, increase the product yield, and improve the purity.一種碘-123-IBZM核醫藥物自動化合成系統,其包含一控制/顯示機構;一連接控制/顯示機構之反應藥劑供給機構;一連接控制/顯示機構與反應藥劑供給機構之吸附機構;一連接控制/顯示機構、反應藥劑供給機構與吸附機構之氧化反應機構;一連接控制/顯示機構、反應藥劑供給機構、吸附機構與氧化反應機構之產品收集機構;一連接控制/顯示機構、吸附機構與產品收集機構之廢液收集機構;以及一連接控制/顯示機構、氧化反應機構與產品收集機構之氣體過濾機構。藉此,可將標幟過程所需之氧化、還原、中和、吸附、清洗、沖提等步驟自動化,縮短操作人員手部操作之時間,而達到輻射暴露劑量少、降低失誤與偏差、穩定產品品質、提高產品產率、以及提供較佳純度之功效。1...控制/顯示機構11...時間控制單元12...反應顯示單元13...反應時間顯示單元14...氣壓設定單元15...壓力顯示單元16...輻射量顯示單元17...停止鍵2...反應藥劑供給機構21...氧化劑瓶22...還原劑瓶23...中和劑瓶24...清洗劑瓶3...吸附機構31...第一吸附管柱32...第二吸附管柱33...第三吸附管柱4...氧化反應機構41...第一氧化反應瓶42...第二氧化反應瓶43...第三氧化反應瓶5...產品收集機構6...廢液收集機構7...氣體過濾機構第1閥體801~第28閥體828
