A surgical clip applier includes an actuation mechanism, a body portion, a jawblade,and a clip cartridge, the jaw blade and clip cartridge removeably disposedwithin the bodyportion. The jaw blade including first and second opposed jaws operablyconnected to theactuation mechanism to effectuate closure of a surgical clip, the first andsecond opposedjaws connected to each other at a proximal end by a shank section. The clipcartridgedisposed within the body portion adjacent to the jaw blade and configured tostore at least onesurgical clip therein. The clip cartridge having a first nub which abuts afirst end of the shanksection of the jaw blade, and a second nub which abuts a second end of theshank section ofthe jaw blade, such that longitudinal and vertical movement of the jaw bladeis arrested.