The present invention relates to a peptidic hydrolyzate enriched in bioactive peptides, said hydrolyzate being a proteasome activator. In addition, the present invention relates to, on the one hand, a cosmetic or pharmaceutical composition comprising said hydrolyzate in a physiologically acceptable medium and, on the other hand, its use to depigment, lighten and/or whiten the skin and prevent or treat hyperpigmentation blemishes as well as cutaneous signs due to photo-aging. Lastly, the invention applies to a cosmetic treatment method utilizing said peptidic hydrolyzate.