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Uridine diphosphate derivatives, prodrugs, compositions and uses thereof
专利权人:
Tufts University
发明人:
Haydon, Philip G.,Lee, Jinbo
申请号:
AU2018202405
公开号:
AU2018202405A1
申请日:
2018.04.05
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2018202405A120180426.pdf#####ABSTRACT This disclosure relates to the use of uridine diphosphate (UDP) derivatives, salts and/or prodrugs thereof for the treatment of inflammatory conditions (e.g., psoriasis) and glaucoma, to prodrugs of UDP derivatives, compositions comprising therapeutically 5 effective amounts of those prodrugs of the UDP derivatives and methods of using those prodrugs for treating various disorders including, e.g., neuronal disorders, including neurodegenerative disorders (e.g., Alzheimer's disease, Parkinson's disease) and traumatic CNS injury, pain, Down Syndrome (DS), glaucoma, and inflammatory conditions, e.g., psoriasis and rheumatoid arthritis.
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