FORMULATIONS TO ACHIEVE RAPID DISSOLUTION OF DRUG FROM SPRAY-DRIED DISPERSIONS IN CAPSULES

• 收藏
• 分享

专利权人:

CAPSUGEL BELGIUM NV

发明人:

MORGEN, MICHAEL MARK,GOODWIN, AARON KEITH

申请号：

CA2987867

公开号：

CA2987867A1

申请日:

2016.05.26

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

Disclosed are dosage forms comprising a capsule and a fill material, comprising (a) a fill material comprising a dispersion of an active agent and a polymer, the dispersion being granulated, (b) an osmogen, and (c) a glidant. In one embodiment, the dispersion comprises 10 wt% to 90 wt% of the fill material, the osmogen comprises from 5 wt% to 40 wt% of the fill material, and the glidant comprises at least 0.1 wt% of the fill material.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/