Boris Schmidt,Daniel Kieser,Alexander Boländer,Jochen Herms,Roland Heyny-Von Haussen,Jiamin Gu
申请号：
US13825186
公开号：
US20130287700A1
申请日:
2011.09.20
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Subject of the present invention are compounds with high affinity for the Aβ protein, α-synuclein or for Tau-PHF aggregates, which are suitable as preferably fluorescent probes for the in vivo diagnosis of neurodegenerative disorders like e.g. Alzheimers disease and Parkinsons disease. The compounds are characterized by suitable physicochemical properties (excitation wavelength, emission wavelength, Stokes shift, extinction) as well as a high affinity and selectivity for the target proteins.
