NOUVEAUX DERIVES DU 1-BENZYL-3-HYDROXYMETHYL-INDAZOLE ET UTILISATION DE CES SUBSTANCES POUR LE TRAITEMENT DE MALADIES BASE SUR L'EXPRESSION DE MCP-1, CX3CR1 ET P40
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.
发明人:
GUGLIELMOTTI, ANGELO,FURLOTTI, GUIDO,MANGANO, GIORGINA,CAZZOLLA, NICOLA,GAROFALO, BARBARA
申请号：
CA2712703
公开号：
CA2712703C
申请日:
2009.03.05
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present invention relates to novel 1-benzyl-3-hydroxymethylindazolederivatives according to formula (I)described in the claims, and to a pharmaceutical composition comprising them,together with a pharmaceutically acceptable vehicle.In addition, the present invention relates to the use of 1-benzyl-3-hydroxymethylindazole derivatives for the preparation of apharmaceutical composition that is active in the treatment of diseases basedon the expression of MCP-1, CX3CR1 and p40, andto their use in a method for treating or preventing diseases based on theexpression of MCP-1, CX3CR1 and p40.
