PAUL SALAMA,RONI MAMLUK,KAREN MAROM,IRINA WEINSTEIN,MOSHE TZABARI
申请号：
GB201119686
公开号：
GB2482810A
申请日:
2009.09.17
申请国别(地区):
GB
年份:
2012
代理人:
摘要：
A pharmaceutical composition comprising a therapeutic agent and at least one salt of a medium chain fatty acid dissolved in a solution comprising essentially a medium chain fatty acid, wherein said medium chain fatty acid has the same fatty acid radical as the said medium chain fatty acid salt. The pharmaceutical compositions described herein are substantially free of alcohol and may be delivered by means of a capsule. Methods of treating or preventing diseases by administering such compositions to affected subjects are also disclosed. A preferred example is disclosed in which the compound exenatide is found to have its bioavailability enhanced by exhibiting a longer release profile when octanoic acid/sodium octanoate is used .
