Shanghai Allist Pharmaceutical and Medical Technology Corporations
发明人:
KUANG, Rongren
申请号:
EP17809655
公开号:
EP3466948A4
申请日:
2017.06.01
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention relates to the fused pyrimidine piperidine cyclic derivative represented by the following formula (I) and a pharmaceutically acceptable salt thereof and a process for preparing the same, wherein R 1 , R 2 , R 3 , R 4 , R 5 , X, Y and Z are defined as in the description. The present invention further provides use of said fused pyrimidine piperidine cyclic derivative in manufacture of a medicament for preventing or treating FGFR kinase mediated disease such as cancer.